Revelation chapters 17 and 18 are an interlude in the sequence of Tribulation events. These chapters deal with the destruction of religious and economic Babylon. Revelation 17 reveals the destruction of Babylon in its religious aspect.
Religion will flourish during the first half of the Tribulation in the false religious system called Babylon, the great prostitute. This system may be centered in the rebuilt city of Babylon or perhaps in Rome. It will be ecumenical including numerous apostate religious groups. This one-world church will enjoy the support of the state and use the power of the state to push its agenda. For the first half of the Tribulation, the prostitute will reign unchallenged; but at the middle of the Tribulation, the Antichrist will see her as a challenge to his own power and program. With the coalition of ten nations under his control, he will destroy the one-world religious system and declare himself God, demanding to be worshiped.